Decoding genomic signatures of metabolic reprograming in diabetes and obesity

Supervisors: Prof. Dr. Henriette Uhlenhaut & Dr. Fabiana Quagliarini

Enrolled since 2021

I completed my Bachelor's Degree in Food Biotechnology at the University of Prishtina and my Master’s Degree in AgriGenomics at the University of Kiel. During my Master’s, I was affiliated with the Institute of Animal Genetics, where I studied bovine microRNAs which controlled genes in cattle that were crucially related to red meat allergy in humans. 

At the end of 2021, I joined the group Molecular Endocrinology of Prof. Uhlenhaut at the Institute of Diabetes and Endocrinology (Helmholtz Zentrum München). My Ph.D. project focuses on studying gene expression alterations that occur in the liver due to nutrition. Nutrition affects a lot of metabolic processes including hormone signaling, which subsequently influences the activation of nuclear receptors. Activated nuclear receptors are able to bind to DNA sequences and control gene regulation. In the case of my project, the aim is to demonstrate the mechanisms of action of a particular nuclear receptor and its coregulators, in response to nutritional status.


  • Fadel L, Dacic M, Fonda V, Sokolsky BA, Quagliarini F, Rogatsky I, Uhlenhaut NH. (2023) Modulating glucocorticoid receptor actions in physiology and pathology: Insights from coregulators. Pharmacol Ther. 251:108531.